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Meiotic arrest with roscovitine and follicular fluid improves cytoplasmic maturation of porcine oocytes by promoting chromatin de-condensation and gene transcription

The developmental capacity of in vitro matured oocytes is inferior to that of the in vivo matured ones due to insufficient cytoplasmic maturation. Although great efforts were made to accomplish better cytoplasmic maturation by meiotic arrest maintenance (MAM) before in vitro maturation (IVM), limite...

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Detalles Bibliográficos
Autores principales: Zhang, Min, Zhang, Chuan-Xin, Pan, Liu-Zhu, Gong, Shuai, Cui, Wei, Yuan, Hong-Jie, Zhang, Wei-Ling, Tan, Jing-He
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599650/
https://www.ncbi.nlm.nih.gov/pubmed/28912491
http://dx.doi.org/10.1038/s41598-017-11970-y