Brain barriers and functional interfaces with sequential appearance of ABC efflux transporters during human development

Adult brain is protected from entry of drugs and toxins by specific mechanisms such as ABC (ATP-binding Cassette) efflux transporters. Little is known when these appear in human brain during development. Cellular distribution of three main ABC transporters (ABCC1, ABCG2, ABCB1) was determined at blo...

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Detalles Bibliográficos
Autores principales: Møllgård, Kjeld, Dziegielewska, Katarzyna M., Holst, Camilla B., Habgood, Mark D., Saunders, Norman R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599687/
https://www.ncbi.nlm.nih.gov/pubmed/28912477
http://dx.doi.org/10.1038/s41598-017-11596-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599687/
https://www.ncbi.nlm.nih.gov/pubmed/28912477
http://dx.doi.org/10.1038/s41598-017-11596-0

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