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Brain barriers and functional interfaces with sequential appearance of ABC efflux transporters during human development
Adult brain is protected from entry of drugs and toxins by specific mechanisms such as ABC (ATP-binding Cassette) efflux transporters. Little is known when these appear in human brain during development. Cellular distribution of three main ABC transporters (ABCC1, ABCG2, ABCB1) was determined at blo...
Autores principales: | Møllgård, Kjeld, Dziegielewska, Katarzyna M., Holst, Camilla B., Habgood, Mark D., Saunders, Norman R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599687/ https://www.ncbi.nlm.nih.gov/pubmed/28912477 http://dx.doi.org/10.1038/s41598-017-11596-0 |
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