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Structural insights into transcription initiation by yeast RNA polymerase I

In eukaryotic cells, RNA polymerase I (Pol I) synthesizes precursor ribosomal RNA (pre‐rRNA) that is subsequently processed into mature rRNA. To initiate transcription, Pol I requires the assembly of a multi‐subunit pre‐initiation complex (PIC) at the ribosomal RNA promoter. In yeast, the minimal PI...

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Detalles Bibliográficos
Autores principales: Sadian, Yashar, Tafur, Lucas, Kosinski, Jan, Jakobi, Arjen J, Wetzel, Rene, Buczak, Katarzyna, Hagen, Wim JH, Beck, Martin, Sachse, Carsten, Müller, Christoph W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599796/
https://www.ncbi.nlm.nih.gov/pubmed/28739580
http://dx.doi.org/10.15252/embj.201796958