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Pressure and stretch differentially affect proliferation of renal proximal tubular cells

Renal obstruction is frequently found in adults and children. Mechanical stimuli, including pressure and stretch in the obstructed kidney, contribute to damage; animal models of obstruction are characterized by increased cellular proliferation. We were interested in the direct effects of pressure an...

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Detalles Bibliográficos
Autores principales: Felsen, Diane, Diaz, Bianca J., Chen, Jie, Gonzalez, Juana, Kristensen, Marie Louise V., Bohn, Anja B., Roth, Brendan T., Poppas, Dix P., Nørregaard, Rikke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599855/
https://www.ncbi.nlm.nih.gov/pubmed/28904080
http://dx.doi.org/10.14814/phy2.13346