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Intracellular Insulin and Impaired Autophagy in a Zebrafish model and a Cell Model of Type 2 diabetes

Type 2 diabetes mellitus is characterized by insulin resistance. However, the complete molecular mechanism remains unclear. In this study, zebrafish were fed a long-term high-fat diet to induce type 2 diabetes, which resulted in a higher body weight, body mass index, more lipid vacuoles in liver, in...

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Detalles Bibliográficos
Autores principales: Meng, Xiang-Hui, Chen, Bo, Zhang, Jing-Pu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599904/
https://www.ncbi.nlm.nih.gov/pubmed/28924380
http://dx.doi.org/10.7150/ijbs.19249