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DNA Methylation Mediated Downregulation of miR-449c Controls Osteosarcoma Cell Cycle Progression by Directly Targeting Oncogene c-Myc

MicroRNAs (miRNAs) are critical regulators of gene expression, and they have broad roles in the pathogenesis of different diseases including cancer. Limited studies and expression profiles of miRNAs are available in human osteosarcoma cells. By applying a miRNA microarray analysis, we observed a num...

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Detalles Bibliográficos
Autores principales: Li, Qing, Li, Hua, Zhao, Xueling, Wang, Bing, Zhang, Lin, Zhang, Caiguo, Zhang, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599909/
https://www.ncbi.nlm.nih.gov/pubmed/28924385
http://dx.doi.org/10.7150/ijbs.19476