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Activation of Nrf2 Attenuates Pulmonary Vascular Remodeling via Inhibiting Endothelial-to-Mesenchymal Transition: an Insight from a Plant Polyphenol

The endothelial-to-mesenchymal transition (EndMT) has been demonstrated to be involved in pulmonary vascular remodeling. It is partly attributed to oxidative and inflammatory stresses in endothelial cells. In current study, we conducted a series of experiments to clarify the effect of salvianolic ac...

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Detalles Bibliográficos
Autores principales: Chen, Yucai, Yuan, Tianyi, Zhang, Huifang, Yan, Yu, Wang, Danshu, Fang, Lianhua, Lu, Yang, Du, Guanhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599911/
https://www.ncbi.nlm.nih.gov/pubmed/28924387
http://dx.doi.org/10.7150/ijbs.20316