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Geraniin inhibits TNF-α-induced impairments of osteogenesis through NF-κB and p38 MAPK signalling pathways in bone marrow stem cells

OBJECTIVE: To study the effect and mechanism of geraniin on the osteogenesis of tumour necrosis factor-alpha (TNF-α)-induced bone marrow-derived mesenchymal stem cells (BMSCs). METHODS: BALB/c mice aged 4–6 weeks were used to collect BMSC. Methyl thiazol tetrazolium assay and lactate dehydrogenase a...

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Detalles Bibliográficos
Autores principales: Lu, Chao, Gao, Shichang, Xu, Ge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600010/
https://www.ncbi.nlm.nih.gov/pubmed/28959491
http://dx.doi.org/10.1136/svn-2016-000046