Worldwide Distribution of Cytochrome P450 Alleles: A Meta‐analysis of Population‐scale Sequencing Projects

Genetic polymorphisms in cytochrome P450 (CYP) genes can result in altered metabolic activity toward a plethora of clinically important medications. Thus, single nucleotide variants and copy number variations in CYP genes are major determinants of drug pharmacokinetics and toxicity and constitute ph...

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Detalles Bibliográficos
Autores principales: Zhou, Y, Ingelman‐Sundberg, M, Lauschke, VM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600063/
https://www.ncbi.nlm.nih.gov/pubmed/28378927
http://dx.doi.org/10.1002/cpt.690

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600063/
https://www.ncbi.nlm.nih.gov/pubmed/28378927
http://dx.doi.org/10.1002/cpt.690

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