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Card9‐dependent IL‐1β regulates IL‐22 production from group 3 innate lymphoid cells and promotes colitis‐associated cancer

Inflammatory bowel diseases (IBD) are key risk factors for the development of colorectal cancer, but the mechanisms that link intestinal inflammation with carcinogenesis are insufficiently understood. Card9 is a myeloid cell‐specific signaling protein that regulates inflammatory responses downstream...

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Detalles Bibliográficos
Autores principales: Bergmann, Hanna, Roth, Susanne, Pechloff, Konstanze, Kiss, Elina A., Kuhn, Sabine, Heikenwälder, Mathias, Diefenbach, Andreas, Greten, Florian R., Ruland, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600091/
https://www.ncbi.nlm.nih.gov/pubmed/28586167
http://dx.doi.org/10.1002/eji.201646765