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Card9‐dependent IL‐1β regulates IL‐22 production from group 3 innate lymphoid cells and promotes colitis‐associated cancer
Inflammatory bowel diseases (IBD) are key risk factors for the development of colorectal cancer, but the mechanisms that link intestinal inflammation with carcinogenesis are insufficiently understood. Card9 is a myeloid cell‐specific signaling protein that regulates inflammatory responses downstream...
Autores principales: | Bergmann, Hanna, Roth, Susanne, Pechloff, Konstanze, Kiss, Elina A., Kuhn, Sabine, Heikenwälder, Mathias, Diefenbach, Andreas, Greten, Florian R., Ruland, Jürgen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600091/ https://www.ncbi.nlm.nih.gov/pubmed/28586167 http://dx.doi.org/10.1002/eji.201646765 |
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