Effect of the Anti‐C1s Humanized Antibody TNT009 and Its Parental Mouse Variant TNT003 on HLA Antibody–Induced Complement Activation—A Preclinical In Vitro Study

The classic pathway (CP) of complement is believed to significantly contribute to alloantibody‐mediated transplant injury, and targeted complement inhibition is currently considered to be a promising approach for preventing rejection. Here, we investigated the mode of action and efficacy of the huma...

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Detalles Bibliográficos
Autores principales: Wahrmann, M., Mühlbacher, J., Marinova, L., Regele, H., Huttary, N., Eskandary, F., Cohen, G., Fischer, G. F., Parry, G. C., Gilbert, J. C., Panicker, S., Böhmig, G. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600102/
https://www.ncbi.nlm.nih.gov/pubmed/28251805
http://dx.doi.org/10.1111/ajt.14256

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600102/
https://www.ncbi.nlm.nih.gov/pubmed/28251805
http://dx.doi.org/10.1111/ajt.14256

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