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Challenging a bioinformatic tool’s ability to detect microbial contaminants using in silico whole genome sequencing data

High sensitivity methods such as next generation sequencing and polymerase chain reaction (PCR) are adversely impacted by organismal and DNA contaminants. Current methods for detecting contaminants in microbial materials (genomic DNA and cultures) are not sensitive enough and require either a known...

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Detalles Bibliográficos
Autores principales: Olson, Nathan D., Zook, Justin M., Morrow, Jayne B., Lin, Nancy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600177/
https://www.ncbi.nlm.nih.gov/pubmed/28924496
http://dx.doi.org/10.7717/peerj.3729