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Challenging a bioinformatic tool’s ability to detect microbial contaminants using in silico whole genome sequencing data
High sensitivity methods such as next generation sequencing and polymerase chain reaction (PCR) are adversely impacted by organismal and DNA contaminants. Current methods for detecting contaminants in microbial materials (genomic DNA and cultures) are not sensitive enough and require either a known...
Autores principales: | Olson, Nathan D., Zook, Justin M., Morrow, Jayne B., Lin, Nancy J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600177/ https://www.ncbi.nlm.nih.gov/pubmed/28924496 http://dx.doi.org/10.7717/peerj.3729 |
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