Multifunctional folate receptor-targeting and pH-responsive nanocarriers loaded with methotrexate for treatment of rheumatoid arthritis

Rheumatoid arthritis (RA) is an autoimmune disease characterized by progressive cartilage and bone destruction. Activated macrophages that overexpress folic acid (FA) receptors play an important role in RA, due to their abundance in inflamed synovial membrane and joints. In an effort to deliver drug...

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Detalles Bibliográficos
Autores principales: Zhao, Jinlong, Zhao, Menghui, Yu, Changhui, Zhang, Xueyan, Liu, Jiaxin, Cheng, Xinwei, Lee, Robert J, Sun, Fengying, Teng, Lesheng, Li, Youxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600269/
https://www.ncbi.nlm.nih.gov/pubmed/28932117
http://dx.doi.org/10.2147/IJN.S140992

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600269/
https://www.ncbi.nlm.nih.gov/pubmed/28932117
http://dx.doi.org/10.2147/IJN.S140992

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