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Chronic exposure of homocysteine in mice contributes to dopamine loss by enhancing oxidative stress in nigrostriatum and produces behavioral phenotypes of Parkinson’s disease

Increased homocysteine (Hcy) level has been implicated as an independent risk factor for various neurological disorders, including Parkinson’s disease (PD). Hcy has been reported to cause dopaminergic neuronal loss in rodents and causes the behavioral abnormalities. This study is an attempt to inves...

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Detalles Bibliográficos
Autores principales: Bhattacharjee, Nivedita, Paul, Rajib, Giri, Anirudha, Borah, Anupom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600271/
https://www.ncbi.nlm.nih.gov/pubmed/28955861
http://dx.doi.org/10.1016/j.bbrep.2016.02.013