Mangiferin attenuates oxidative stress induced renal cell damage through activation of PI3K induced Akt and Nrf-2 mediated signaling pathways

BACKGROUND: Mangiferin is a polyphenolic xanthonoid with remarkable antioxidant activity. Oxidative stress plays the key role in tert-butyl hydroperoxide (tBHP) induced renal cell damage. In this scenario, we consider mangiferin, as a safe agent in tBHP induced renal cell death and rationalize its a...

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Detalles Bibliográficos
Autores principales: Saha, Sukanya, Sadhukhan, Pritam, Sinha, Krishnendu, Agarwal, Namrata, Sil, Parames C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600319/
https://www.ncbi.nlm.nih.gov/pubmed/28955838
http://dx.doi.org/10.1016/j.bbrep.2016.01.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600319/
https://www.ncbi.nlm.nih.gov/pubmed/28955838
http://dx.doi.org/10.1016/j.bbrep.2016.01.011

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