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Mangiferin attenuates oxidative stress induced renal cell damage through activation of PI3K induced Akt and Nrf-2 mediated signaling pathways

BACKGROUND: Mangiferin is a polyphenolic xanthonoid with remarkable antioxidant activity. Oxidative stress plays the key role in tert-butyl hydroperoxide (tBHP) induced renal cell damage. In this scenario, we consider mangiferin, as a safe agent in tBHP induced renal cell death and rationalize its a...

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Detalles Bibliográficos
Autores principales:	Saha, Sukanya, Sadhukhan, Pritam, Sinha, Krishnendu, Agarwal, Namrata, Sil, Parames C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600319/ https://www.ncbi.nlm.nih.gov/pubmed/28955838 http://dx.doi.org/10.1016/j.bbrep.2016.01.011

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