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Diallyl disulfide ameliorates isoproterenol induced cardiac hypertrophy activating mitochondrial biogenesis via eNOS-Nrf2-Tfam pathway in rats

The beneficial effect of garlic on cardiovascular disease is well known. However, the use of raw garlic against cardiac hypertrophy is not established. In the present study we explored whether raw garlic and its compound, diallyl disulfide (DADS) could inhibit hypertrophy through H(2)S and/or mitoch...

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Detalles Bibliográficos
Autores principales: Khatua, Tarak Nath, Dinda, Amit K., Putcha, Uday K., Banerjee, Sanjay K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600345/
https://www.ncbi.nlm.nih.gov/pubmed/28955809
http://dx.doi.org/10.1016/j.bbrep.2015.11.008