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Up-regulation of Syndecan-4 contributes to TGF-β1-induced epithelial to mesenchymal transition in lung adenocarcinoma A549 cells

Syndecan-4 (SDC4) is a cell-surface proteoglycan associated with cell adhesion, motility, and intracellular signaling. Here, we present that SDC4 functions as a positive regulator of the transforming growth factor (TGF)-β1-induced epithelial to mesenchymal transition (EMT) via Snail in lung adenocar...

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Detalles Bibliográficos
Autores principales: Toba-Ichihashi, Yoko, Yamaoka, Toshimitsu, Ohmori, Tohru, Ohba, Motoi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600357/
https://www.ncbi.nlm.nih.gov/pubmed/28955801
http://dx.doi.org/10.1016/j.bbrep.2015.11.021