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Inflammatory cytokine production in tumor cells upon chemotherapy drug exposure or upon selection for drug resistance

Tumor Necrosis Factor alpha (TNF-α) has been shown to be released by tumor cells in response to docetaxel, and lipopolysaccharides (LPS), the latter through activation of toll-like receptor 4 (TLR4). However, it is unclear whether the former involves TLR4 receptor activation through direct binding o...

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Detalles Bibliográficos
Autores principales: Edwardson, Derek W., Boudreau, Justin, Mapletoft, Jonathan, Lanner, Carita, Kovala, A. Thomas, Parissenti, Amadeo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600395/
https://www.ncbi.nlm.nih.gov/pubmed/28915246
http://dx.doi.org/10.1371/journal.pone.0183662