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Complicated behavior of G-quadruplexes and evaluating G-quadruplexes' ligands in various systems mimicking cellular circumstance

Environments surrounding G-rich sequences remarkably affect the conformations of these structures. A proper evaluation system mimicking the crowded environment in a cell with macromolecules should be developed to perform structural and functional studies on G-quadruplexes. In this study, the topolog...

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Detalles Bibliográficos
Autores principales: Wang, Shi-Ke, Su, Hua-Fei, Gu, Yu-Chao, Lin, Shu-Ling, Tan, Jia-Heng, Huang, Zhi-Shu, Ou, Tian-Miao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600415/
https://www.ncbi.nlm.nih.gov/pubmed/28955851
http://dx.doi.org/10.1016/j.bbrep.2015.09.022