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Exploring potential anticoagulant drug formulations using thrombin generation test

Many anticoagulant drugs inhibiting proteins of the coagulation cascade have been developed. The main targets of anticoagulant drugs are thrombin and factor Xa; inhibiting these factors delays thrombus growth, thus preventing thrombosis while increasing bleeding risk. A balance between thrombosis an...

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Detalles Bibliográficos
Autores principales: Zavyalova, Elena, Kopylov, Alexey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600416/
https://www.ncbi.nlm.nih.gov/pubmed/28955812
http://dx.doi.org/10.1016/j.bbrep.2015.11.011