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The inhibitors of cyclin-dependent kinases and GSK-3β enhance osteoclastogenesis
Osteoclasts are multinucleated cells with bone resorption activity that is crucial for bone remodeling. RANK‐RANKL (receptor activator of nuclear factor κB ligand) signaling has been shown as a main signal pathway for osteoclast differentiation. However, the molecular mechanism and the factors regul...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600418/ https://www.ncbi.nlm.nih.gov/pubmed/28955831 http://dx.doi.org/10.1016/j.bbrep.2015.12.011 |