Cargando…
The inhibitors of cyclin-dependent kinases and GSK-3β enhance osteoclastogenesis
Osteoclasts are multinucleated cells with bone resorption activity that is crucial for bone remodeling. RANK‐RANKL (receptor activator of nuclear factor κB ligand) signaling has been shown as a main signal pathway for osteoclast differentiation. However, the molecular mechanism and the factors regul...
Autores principales: | Akiba, Yosuke, Mizuta, Akiko, Kakihara, Yoshito, Nakata, Juri, Nihara, Jun, Saito, Isao, Egusa, Hiroshi, Saeki, Makio |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600418/ https://www.ncbi.nlm.nih.gov/pubmed/28955831 http://dx.doi.org/10.1016/j.bbrep.2015.12.011 |
Ejemplares similares
-
Exosome-Bound WD Repeat Protein Monad Inhibits Breast Cancer Cell Invasion by Degrading Amphiregulin mRNA
por: Saeki, Makio, et al.
Publicado: (2013) -
R2TP/PAQosome as a promising chemotherapeutic target in cancer
por: Kakihara, Yoshito, et al.
Publicado: (2020) -
Preclinical models of deep craniofacial nociception and temporomandibular disorder pain
por: Okamoto, Keiichiro, et al.
Publicado: (2021) -
PKCβ Positively Regulates RANKL-Induced Osteoclastogenesis by Inactivating GSK-3β
por: Shin, Jihye, et al.
Publicado: (2014) -
Extracellular Matrix-Oriented Proteomic Analysis of Periodontal Ligament Under Mechanical Stress
por: Thant, Lay, et al.
Publicado: (2022)