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CD44 induced enhancement of phosphatase activity and calcium influx: Modifications of EGR-1 expression and cell proliferation

The purpose of this study was to investigate how CD44 impaired Akt phosphorylation, EGR-1 expression and cell proliferation. E6.1 Jurkat cells, which lack endogenous CD44 expression, were engineered to express CD44. Previously we showed that Akt is hypophosphorylated, EGR-1 expression is reduced and...

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Detalles Bibliográficos
Autores principales: Racine, Ronny R., Manalo, Nathan A., Hall, Jessica M.F., Dibas, Adnan, Raffel, Glen D., Mummert, Mark E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600419/
https://www.ncbi.nlm.nih.gov/pubmed/28955875
http://dx.doi.org/10.1016/j.bbrep.2016.03.016