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Inhibitory efficacy of bufadienolides on Na(+),K(+)-pump activity versus cell proliferation
Bufadienolides are cytotoxic drugs that may form the basis for anticancer agents. Due to structural and functional similarity to cardiotonic glycosides, application is restricted. We, therefore, investigated correlation of their putative anticancer effects with inhibition of Na(+),K(+)pumps. The nat...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600443/ https://www.ncbi.nlm.nih.gov/pubmed/28955873 http://dx.doi.org/10.1016/j.bbrep.2016.03.015 |