A soluble form of human nectin-2 impairs exocrine secretion of pancreas and formation of zymogen granules in transgenic mice

Transgenic mouse lines expressing a soluble form of human nectin-2 (hNectin-2Ig Tg) exhibited distinctive elevation of amylase and lipase levels in the sera. In this study, we aimed to clarify the histopathology and to propose the transgenic mouse lines as new animal model for characteristic pancrea...

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Detalles Bibliográficos
Autores principales: Tomioka, Yukiko, Fujimoto, Yoshikazu, Nakai, Kanji, Ozaki, Kinuyo, Yamamoto, Sayo, Suyama, Haruka, Morimatsu, Masami, Ito, Toshihiro, Ono, Etsuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600445/
https://www.ncbi.nlm.nih.gov/pubmed/28955824
http://dx.doi.org/10.1016/j.bbrep.2015.12.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600445/
https://www.ncbi.nlm.nih.gov/pubmed/28955824
http://dx.doi.org/10.1016/j.bbrep.2015.12.006

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