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Interacting mechanism of ID3 HLH domain towards E2A/E12 transcription factor – An Insight through molecular dynamics and docking approach

Inhibitor of DNA binding protein 3 (ID3) has long been characterized as an oncogene that implicates its functional role through its Helix–Loop–Helix (HLH) domain upon protein–protein interaction. An insight into the dimerization brought by this domain helps in identifying the key residues that favor...

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Detalles Bibliográficos
Autores principales: Topno, Nishith Saurav, Kannan, Muthu, Krishna, Ramadas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600450/
https://www.ncbi.nlm.nih.gov/pubmed/28955822
http://dx.doi.org/10.1016/j.bbrep.2015.12.002