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Chimeric Antigen Receptor-Redirected Regulatory T Cells Suppress Experimental Allergic Airway Inflammation, a Model of Asthma

Cellular therapy with chimeric antigen receptor (CAR)-redirected cytotoxic T cells has shown impressive efficacy in the treatment of hematologic malignancies. We explored a regulatory T cell (Treg)-based therapy in the treatment of allergic airway inflammation, a model for asthma, which is character...

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Detalles Bibliográficos
Autores principales: Skuljec, Jelena, Chmielewski, Markus, Happle, Christine, Habener, Anika, Busse, Mandy, Abken, Hinrich, Hansen, Gesine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600908/
https://www.ncbi.nlm.nih.gov/pubmed/28955341
http://dx.doi.org/10.3389/fimmu.2017.01125