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In Vitro and In Vivo Biocompatibility Evaluation of Polyallylamine and Macromolecular Heparin Conjugates Modified Alginate Microbeads

Host reactivity to biocompatible immunoisolation devices is a major challenge for cellular therapies, and a human screening model would be of great value. We designed new types of surface modified barium alginate microspheres, and evaluated their inflammatory properties using human whole blood, and...

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Detalles Bibliográficos
Autores principales: Vaithilingam, Vijayaganapathy, Steinkjer, Bjørg, Ryan, Liv, Larsson, Rolf, Tuch, Bernard Edward, Oberholzer, Jose, Rokstad, Anne Mari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600981/
https://www.ncbi.nlm.nih.gov/pubmed/28916826
http://dx.doi.org/10.1038/s41598-017-11989-1