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Hormetic potential of methylglyoxal, a side-product of glycolysis, in switching tumours from growth to death

Metabolic reprogramming toward aerobic glycolysis unavoidably favours methylglyoxal (MG) and advanced glycation end products (AGEs) formation in cancer cells. MG was initially considered a highly cytotoxic molecule with potential anti-cancer value. However, we have recently demonstrated that MG enha...

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Detalles Bibliográficos
Autores principales: Nokin, Marie-Julie, Durieux, Florence, Bellier, Justine, Peulen, Olivier, Uchida, Koji, Spiegel, David A., Cochrane, James R., Hutton, Craig A., Castronovo, Vincent, Bellahcène, Akeila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600983/
https://www.ncbi.nlm.nih.gov/pubmed/28916747
http://dx.doi.org/10.1038/s41598-017-12119-7