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Hormetic potential of methylglyoxal, a side-product of glycolysis, in switching tumours from growth to death
Metabolic reprogramming toward aerobic glycolysis unavoidably favours methylglyoxal (MG) and advanced glycation end products (AGEs) formation in cancer cells. MG was initially considered a highly cytotoxic molecule with potential anti-cancer value. However, we have recently demonstrated that MG enha...
Autores principales: | Nokin, Marie-Julie, Durieux, Florence, Bellier, Justine, Peulen, Olivier, Uchida, Koji, Spiegel, David A., Cochrane, James R., Hutton, Craig A., Castronovo, Vincent, Bellahcène, Akeila |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600983/ https://www.ncbi.nlm.nih.gov/pubmed/28916747 http://dx.doi.org/10.1038/s41598-017-12119-7 |
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