Synthesis, Molecular Properties Estimations, and Dual Dopamine D(2) and D(3) Receptor Activities of Benzothiazole-Based Ligands

Neurleptic drugs, e.g., aripiprazole, targeting the dopamine D(2S) and D(3) receptors (D(2S)R and D(3)R) in the central nervous system are widely used in the treatment of several psychotic and neurodegenerative diseases. Therefore, a new series of benzothiazole-based ligands (3-20) was synthesized b...

Descripción completa

Detalles Bibliográficos
Autores principales: Schübler, Moritz, Sadek, Bassem, Kottke, Tim, Weizel, Lilia, Stark, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601007/
https://www.ncbi.nlm.nih.gov/pubmed/28955709
http://dx.doi.org/10.3389/fchem.2017.00064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601007/
https://www.ncbi.nlm.nih.gov/pubmed/28955709
http://dx.doi.org/10.3389/fchem.2017.00064

Ejemplares similares