Cooperative but distinct early co-signaling events originate from ERBB2 and ERBB1 receptors upon trastuzumab treatment in breast cancer cells

ERBB2 receptor belongs to the ERBB tyrosine kinase receptor family. At variance to the other family members, ERBB2 is a constitutively active orphan receptor. Upon ligand binding and activation, ERBB receptors form homo- or hetero-dimers with the other family members, including ERBB2, promoting an i...

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Detalles Bibliográficos
Autores principales: Bagnato, Paola, Castagnino, Alessia, Cortese, Katia, Bono, Maria, Grasso, Silvia, Bellese, Grazia, Daniele, Tiziana, Lundmark, Richard, Defilippi, Paola, Castagnola, Patrizio, Tacchetti, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601125/
https://www.ncbi.nlm.nih.gov/pubmed/28947957
http://dx.doi.org/10.18632/oncotarget.17686

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601125/
https://www.ncbi.nlm.nih.gov/pubmed/28947957
http://dx.doi.org/10.18632/oncotarget.17686

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