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TNFα affects CREB-mediated neuroprotective signaling pathways of synaptic plasticity in neurons as revealed by proteomics and phospho-proteomics

Neuroinflammation is a hallmark of Alzheimer's disease and TNFα as the main inducer of neuroinflammation has neurodegenerative but also pro-regenerative properties, however, the dose-dependent molecular changes on signaling pathway level are not fully understood. We performed quantitative prote...

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Detalles Bibliográficos
Autores principales: Jensen, Pia, Myhre, Christa L., Lassen, Pernille S., Metaxas, Athanasios, Khan, Asif M., Lambertsen, Kate L., Babcock, Alicia A., Finsen, Bente, Larsen, Martin R., Kempf, Stefan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601134/
https://www.ncbi.nlm.nih.gov/pubmed/28947966
http://dx.doi.org/10.18632/oncotarget.19428