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TNFα affects CREB-mediated neuroprotective signaling pathways of synaptic plasticity in neurons as revealed by proteomics and phospho-proteomics
Neuroinflammation is a hallmark of Alzheimer's disease and TNFα as the main inducer of neuroinflammation has neurodegenerative but also pro-regenerative properties, however, the dose-dependent molecular changes on signaling pathway level are not fully understood. We performed quantitative prote...
Autores principales: | Jensen, Pia, Myhre, Christa L., Lassen, Pernille S., Metaxas, Athanasios, Khan, Asif M., Lambertsen, Kate L., Babcock, Alicia A., Finsen, Bente, Larsen, Martin R., Kempf, Stefan J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601134/ https://www.ncbi.nlm.nih.gov/pubmed/28947966 http://dx.doi.org/10.18632/oncotarget.19428 |
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