PGC1α induced by reactive oxygen species contributes to chemoresistance of ovarian cancer cells

Malignant cells are subjected to high levels of oxidative stress that arise from the increased production of reactive oxygen species (ROS) due to their altered metabolism. They activate antioxidant mechanisms to relieve the oxidative stress, and thereby acquire resistance to chemotherapeutic agents....

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Detalles Bibliográficos
Autores principales: Kim, Boyun, Jung, Je Won, Jung, Jaeyoung, Han, Youngjin, Suh, Dong Hoon, Kim, Hee Seung, Dhanasekaran, Danny N., Song, Yong Sang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601140/
https://www.ncbi.nlm.nih.gov/pubmed/28947972
http://dx.doi.org/10.18632/oncotarget.19140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601140/
https://www.ncbi.nlm.nih.gov/pubmed/28947972
http://dx.doi.org/10.18632/oncotarget.19140

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