Phenformin inhibits growth and epithelial-mesenchymal transition of ErbB2-overexpressing breast cancer cells through targeting the IGF1R pathway

Reports suggest that metformin, a popular anti-diabetes drug, prevents breast cancer through various systemic effects, including insulin-like growth factor receptor (IGFR) regulation. Although the anti-cancer properties of metformin have been well-studied, reports on a more bioavailable/potent bigua...

Descripción completa

Detalles Bibliográficos
Autores principales: Guo, Zhiying, Zhao, Ming, Howard, Erin W., Zhao, Qingxia, Parris, Amanda B., Ma, Zhikun, Yang, Xiaohe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601143/
https://www.ncbi.nlm.nih.gov/pubmed/28947975
http://dx.doi.org/10.18632/oncotarget.19466

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601143/
https://www.ncbi.nlm.nih.gov/pubmed/28947975
http://dx.doi.org/10.18632/oncotarget.19466

Ejemplares similares