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Phenformin inhibits growth and epithelial-mesenchymal transition of ErbB2-overexpressing breast cancer cells through targeting the IGF1R pathway

Reports suggest that metformin, a popular anti-diabetes drug, prevents breast cancer through various systemic effects, including insulin-like growth factor receptor (IGFR) regulation. Although the anti-cancer properties of metformin have been well-studied, reports on a more bioavailable/potent bigua...

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Detalles Bibliográficos
Autores principales:	Guo, Zhiying, Zhao, Ming, Howard, Erin W., Zhao, Qingxia, Parris, Amanda B., Ma, Zhikun, Yang, Xiaohe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601143/ https://www.ncbi.nlm.nih.gov/pubmed/28947975 http://dx.doi.org/10.18632/oncotarget.19466

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