Generation of a novel Antibody-Drug Conjugate targeting endosialin: potent and durable antitumor response in sarcoma

The endosialin/CD248/TEM1 receptor is expressed on the cell surface of tumor-associated stroma cells as well as in sarcoma and neuroblastoma cells. This receptor is emerging as an attractive molecule in diagnostics and therapeutics because of its expression across the stroma of many human tumors, th...

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Detalles Bibliográficos
Autores principales: Capone, Emily, Piccolo, Enza, Fichera, Imma, Ciufici, Paolo, Barcaroli, Daniela, Sala, Arturo, De Laurenzi, Vincenzo, Iacobelli, Valentina, Iacobelli, Stefano, Sala, Gianluca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601145/
https://www.ncbi.nlm.nih.gov/pubmed/28947977
http://dx.doi.org/10.18632/oncotarget.19499

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601145/
https://www.ncbi.nlm.nih.gov/pubmed/28947977
http://dx.doi.org/10.18632/oncotarget.19499

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