Uptake and metabolism of sulphated steroids by the blood–brain barrier in the adult male rat

Little is known about the origin of the neuroactive steroids dehydroepiandrosterone sulphate (DHEAS) and pregnenolone sulphate (PregS) in the brain or of their subsequent metabolism. Using rat brain perfusion in situ, we have found (3)H‐PregS to enter more rapidly than (3)H‐DHEAS and both to undergo...

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Detalles Bibliográficos
Autores principales: Qaiser, M. Zeeshan, Dolman, Diana E. M., Begley, David J., Abbott, N. Joan, Cazacu‐Davidescu, Mihaela, Corol, Delia I., Fry, Jonathan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
ORIGINAL ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601180/
https://www.ncbi.nlm.nih.gov/pubmed/28665486
http://dx.doi.org/10.1111/jnc.14117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601180/
https://www.ncbi.nlm.nih.gov/pubmed/28665486
http://dx.doi.org/10.1111/jnc.14117

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