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Uptake and metabolism of sulphated steroids by the blood–brain barrier in the adult male rat
Little is known about the origin of the neuroactive steroids dehydroepiandrosterone sulphate (DHEAS) and pregnenolone sulphate (PregS) in the brain or of their subsequent metabolism. Using rat brain perfusion in situ, we have found (3)H‐PregS to enter more rapidly than (3)H‐DHEAS and both to undergo...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601180/ https://www.ncbi.nlm.nih.gov/pubmed/28665486 http://dx.doi.org/10.1111/jnc.14117 |