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Fine‐tuning PERK signaling for neuroprotection

Protein translation and folding are tightly controlled processes in all cells, by proteostasis, an important component of which is the unfolded protein response (UPR). During periods of endoplasmic reticulum stress because of protein misfolding, the UPR activates a coordinated response in which the...

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Detalles Bibliográficos
Autores principales: Halliday, Mark, Hughes, Daniel, Mallucci, Giovanna R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601187/
https://www.ncbi.nlm.nih.gov/pubmed/28643372
http://dx.doi.org/10.1111/jnc.14112