Cargando…

Divergent Synthesis of Cyclopropane‐Containing Lead‐Like Compounds, Fragments and Building Blocks through a Cobalt Catalyzed Cyclopropanation of Phenyl Vinyl Sulfide

Cyclopropanes provide important design elements in medicinal chemistry and are widely present in drug compounds. Here we describe a strategy and extensive synthetic studies for the preparation of a diverse collection of cyclopropane‐containing lead‐like compounds, fragments and building blocks explo...

Descripción completa

Detalles Bibliográficos
Autores principales: Chawner, Stephen J., Cases‐Thomas, Manuel J., Bull, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601191/
https://www.ncbi.nlm.nih.gov/pubmed/28983191
http://dx.doi.org/10.1002/ejoc.201701030