Curtailed T‐cell activation curbs effector differentiation and generates CD8(+) T cells with a naturally‐occurring memory stem cell phenotype

Human T memory stem (T(SCM)) cells with superior persistence capacity and effector functions are emerging as important players in the maintenance of long‐lived T‐cell memory and are thus considered an attractive population to be used in adoptive transfer‐based immunotherapy of cancer. However, the m...

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Detalles Bibliográficos
Autores principales: Zanon, Veronica, Pilipow, Karolina, Scamardella, Eloise, De Paoli, Federica, De Simone, Gabriele, Price, David A., Martinez Usatorre, Amaia, Romero, Pedro, Mavilio, Domenico, Roberto, Alessandra, Lugli, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Adaptive immunity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601228/
https://www.ncbi.nlm.nih.gov/pubmed/28671275
http://dx.doi.org/10.1002/eji.201646732

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601228/
https://www.ncbi.nlm.nih.gov/pubmed/28671275
http://dx.doi.org/10.1002/eji.201646732

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