Structure of Human Tyrosinase Related Protein 1 Reveals a Binuclear Zinc Active Site Important for Melanogenesis

Tyrosinase‐related protein 1 (TYRP1) is one of three tyrosinase‐like glycoenzymes in human melanocytes that are key to the production of melanin, the compound responsible for the pigmentation of skin, eye, and hair. Difficulties with producing these enzymes in pure form have hampered the understandi...

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Detalles Bibliográficos
Autores principales: Lai, Xuelei, Wichers, Harry J., Soler‐Lopez, Montserrat, Dijkstra, Bauke W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601231/
https://www.ncbi.nlm.nih.gov/pubmed/28661582
http://dx.doi.org/10.1002/anie.201704616

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601231/
https://www.ncbi.nlm.nih.gov/pubmed/28661582
http://dx.doi.org/10.1002/anie.201704616

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