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MacroEvoLution: A New Method for the Rapid Generation of Novel Scaffold‐Diverse Macrocyclic Libraries

Macrocycles are a structural class bearing great promise for future challenges in medicinal chemistry. Nevertheless, there are few flexible approaches for the rapid generation of structurally diverse macrocyclic compound collections. Here, an efficient method for the generation of novel macrocyclic...

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Detalles Bibliográficos
Autores principales: Saupe, Jörn, Kunz, Oliver, Haustedt, Lars Ole, Jakupovic, Sven, Mang, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601232/
https://www.ncbi.nlm.nih.gov/pubmed/28715083
http://dx.doi.org/10.1002/chem.201703209