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In vivo characterisation of a therapeutically relevant self‐assembling (18)F‐labelled β‐sheet forming peptide and its hydrogel using positron emission tomography

Positron emission tomography (PET) and fluorescence labelling have been used to assess the pharmacokinetics, biodistribution and eventual fate of a hydrogel‐forming nonapeptide, FEFKFEFKK (F9), in healthy mice, using (18)F‐labelled and fluorescein isothiocyanate (FITC)‐labelled F9 analogues. F9 was...

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Detalles Bibliográficos
Autores principales: Morris, O., Elsawy, M.A., Fairclough, M., Williams, K.J., Mcmahon, A., Grigg, J., Forster, D., Miller, A.F., Saiani, A., Prenant, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601235/
https://www.ncbi.nlm.nih.gov/pubmed/28623878
http://dx.doi.org/10.1002/jlcr.3534